covid-19

ワクチン接種完了なら屋外でマスク不要、米CDCが指針

t.taka 2021-05-11 1,342件のコメント

《記事要約》

米疾病対策センター（CDC）は4月27日、ワクチン接種を終えた人々についてのガイドラインを新たに発表し、
どのような屋外活動が安全かを明確にした。判定は？　ワクチン接種を終えた人は相手がワクチン接種を受けたかどうかにかかわらず、
屋外での小規模の集まりや食事でマスクを外しても大丈夫というものだ。

「ワクチン接種を受けた人は、ほとんどの場合、マスクなしで屋外活動しても安全です」と、
CDCのロシェル・ワレンスキー所長は27日、ホワイトハウスでの記者会見で説明した。

「マスク着用者が減少すれば、ワクチン接種を受けていない人が、自分もマスクを着用する必要はないと感じるかもしれません。
マスク着用の社会的圧力は間違いなく低下するでしょう」

混乱の可能性こそあるものの、この新しいガイドラインは間違いなく、パンデミックが到来してからずっと我慢してきた人々、
夏の日差しを浴びることが精神的な励みになる人々に、喉から手が出るほどほしかった新たな保証を与えるだろう。

元記事：https://natgeo.nikkeibp.co.jp/atcl/news/21/050600217/

　

ネットの反応

　

米は州によって接種率のばらつきがあるようだしね。
前回引っ込めた時は明らかに早すぎたが、今回は微妙かな。

　

ワクチン打っても感染者や死者がどんどん出てるのに何を言ってるんだ

　

欧米はなんでそんなにマスク付けるの嫌がるんだろうな

　

これだからアメリカ人は、アホなんだよ

　

屋外だからな
勘違いして施設内でマスク取るなよお前ら

　

花粉症にならないし風邪も引かなかったから俺はマスク続けるよ

　

日本だとワクチン接種が進んでも
まだ、ここまで楽観視できないでしょうね。

　

夏でもマスクありの世界は俺が待ち望んでいたものだ
もしもパンデミックが過ぎ去っても俺は通年マスクマンとして生き抜いてやる

　

一日中外で遊んだり運動ばっかしてたらがっつりマスク焼けしたわ
イケメンでもブサイクになるわマスク焼け

　

俺は口臭が臭いからマスクをつけたい

　

アメリカは新型コロナウイルスと共存する選択をした。
収束は不可能だから共存すると。

　

欧米はマスク外す流れだな
かつて日本人は皆マスク着用して褒められてたのが
今度はいまだにマスクが必要な危険な国扱いされるのか

　

マスクは未来永劫着用義務だ
パンツと一緒

　

すでに公園とかビーチとか、
もうマスクしてない人の方が多いですけどね。

最初はマスクに違和感もあったけど、
すっかり慣れたから今だとマスク無しだと
逆に不安だわ。

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  786. With that stated, while creatine HCL is claimed to have higher bioavailability, because of the hydrochloride, and your stomach, contains hydrochloric acid. Creatine HCL is extra soluble in water than creatine monohydrate, nonetheless once exposed to the hydrochloric acid in your abdomen, acid has been proven to extend creatine solubility, making creatine monohydrate steady in stomach acid. Finally, the true good factor about a creatine loading section is dependent upon the time frame in which you’re making an attempt to succeed in your objectives. It can also be ingested through sure foods, together with beef, pork, hen, fish, eggs, another animal-based products, and pumpkin seeds. Twenty-four elite athletes from the Bulgarian National Weightlifting Staff have been chosen to take part in a double-blind medical examine evaluating Kre Alkalyn to plain creatine monohydrate.
    Based on all the scientific information, our choice of one of the best form of creatine supplement is – creatine monohydrate. It is the secure, inexpensive, and handiest kind of creatine obtainable available within the market. Creatine monohydrate is taken into account because the purest form of creatine available in the market.
    Creatine ingested via supplementation is transported into the cells completely by CreaT1. Nevertheless, there’s one other creatine transporter Crea T2, which is primarily energetic and present within the testes [12]. Creatine uptake is regulated by various mechanisms, specifically phosphorylation and glycosylation as well as extracellular and intracellular ranges of creatine.
    We think about the training standing of our participants a power of this examine as a outcome of we included solely skilled cyclists with competitive expertise. Additionally, participants had been experienced in dash biking in training and/or competitors. The familiarization earlier than baseline testing additional improves the quality of our outcomes as a outcome of reliability improves when a familiarization is undertaken [8,34].
    The supernatant was transferred into a pre-weighed microfuge tube and neutralized with 2.1 M KHCO3/0.three M MOPS answer. The samples were then centrifuged once more at 7,000 rpm for 5 minutes and the supernatant was removed and placed into microfuge tubes and frozen at −80°C. As a result, we will count on to see effects much like what we get with monohydrate.
    While creatine retention was significantly larger within the CM and dextrose group, no significant differences were seen between the CM and effervescent TCC groups. These findings suggest that while consuming a relatively small quantity of dextrose with CM can enhance entire physique creatine retention, supplementation of TCC in an effervescent type doesn’t augment whole physique creatine retention greater than CM alone (Fig. 9). As an introduction about creatine’s potential role in well being and disease, the next supplies a common overview of creatine’s metabolic function, purported benefits all through the lifespan, and potential therapeutic functions. Additionally, we provide affordable conclusions in regards to the state of the science on creatine supplementation. We hope that this evaluate and special problem will assist readers and medical practitioners better perceive the security and efficacy of creatine supplementation in a variety of populations and provide suggestions about future research wants. Those who want to quickly increase muscle creatine content material could think about what’s often known as a loading part.
    Given the metabolic function of creatine and the PCR/CK system, significantly throughout ischemia and in some illness states, there has been interest in inspecting the potential therapeutic role of creatine in a variety of clinical populations. The following provides a quick overview of some of this work as an introduction to subjects that shall be reviewed in greater detail in different papers in this special problem. I share my fitness coaching experience in addition to the sports science research I’ve carried out on the many benefits power building, train, & good consuming habits provide us. Since research present creatine does not seem to have an impact on insulin ranges, many nutrition and health experts agree that taking it should not technically break a quick, although everybody’s physique is exclusive. First I found that Creapure even existed and then I immediately immersed into learning about how it’s made with super strict standards, and the way it’s the standard type utilized in creatine sports activities & muscular performance studies. In summary, Creapure isn’t just a fancier model of creatine monohydrate; it’s a meticulously crafted, rigorously tested, and highly trusted product that takes the guesswork out of supplementation. Manufactured by Alzchem Trostberg GmbH in Germany, Creapure is made from creatine monohydrate, the most used and most studied type of creatine globally.
    Little analysis supports these assertions directly, but arginine’s NO-boosting impact improves muscle development in younger rats, whereas KIC and AKG have muscle-building or muscle-supporting results of their own. It’s certainly plausible that these (and possibly other) NO supplement combos could enhance pump or muscle mass for some. Moreover, the solubility of creatine monohydrate dietary supplements is poor in comparison with Kre-Alkalyn, which dissolves completely in water and is taken into account superior on this regard. As is the case with many dietary supplements, the benefits that come with frequently taking creatine will not be permanent.
    These strategies look like probably the most efficient method of saturating the muscle tissue and benefitting from CM supplementation. Nevertheless more modern analysis has proven CM supplementation at doses of zero.1 g/kg body weight combined with resistance coaching improves training variations at a mobile and sub-cellular level. Creatine retention by the physique from supplementation appears to be promoted by about 25% from the simultaneous ingestion of carbohydrate and/or protein mediated via a rise in insulin secretion. This combination would produce a faster saturation fee but has not been shown to have a greater effect on performance. Creatine is a hydrophilic polar molecule that consists of a negatively charged carboxyl group and a positively charged useful group [64].
    Just Lately, Braggion et al. [67] additionally observed that coaching carried out on a ladder (3×/week for 12 weeks) increased collagen fibers in the soleus skeletal muscle of ovariectomized rats. The upregulation of collagen turnover due to prolonged training might be attributable to the elevated activity of fibroblasts concerned in muscle hypertrophy and regeneration [67,68]. This change may present mechanical help to muscle fibers, as resistance training promotes a excessive contractile demand to a quantity of skeletal muscle tissue, despite totally different histological, biochemical, and metabolic properties [51]. The study may lack adequate energy to detect a significant impact of 15-s work relative to FFM.
    The working muscular tissues rapidly synthesize ATP from ADP with creatine phosphate as a cofactor, helping your muscle tissue generate extra force or pace. Deldicque et al [32] discovered a 250%, 45% and 70% improve for collagen mRNA, glucose transporter 4 (GLUT4) and Myosin heavy chain IIA, respectively after 5 days creatine loading protocol (21 g/d). The authors speculated that creatine in addition to a single bout of resistance training can favor an anabolic environment by inducing adjustments in gene expression after only 5 days of supplementation.
    At the top of the experimental protocol, train training intervention resulted in a decrease final physique weight; Tc exhibited lowered physique weight when compared to the Cc and Tcr teams. Feed efficiency was lower in Tc and Tcr than Cc and Cr, respectively, and was greater in Cr than Cc. All skilled rats were familiarized with the climbing exercise protocol for 3 days with a 10% animal physique weight load. A total of eight to 12 climbing units had been thought-about a complete session during familiarization [36,37]. Latest research [7,21] determined the energetic contribution of the phosphagen, glycolytic, and cardio pathways to a 15-s all-out sprint. For this kind of indirect evaluation, phosphagen contribution is determined via fuel change measurements, including OffV˙ O2 kinetics, whereas glycolytic contribution is inferred from adjustments in capillary blood lactate focus [7]. Particularly glycolytic contribution is carefully linked to power output during the 15-s all-out sprint test [22].
    Although there’s less research obtainable on creatine HCL compared to monohydrate, preliminary studies and anecdotal proof recommend that it could require a lower dosage to realize related benefits as a end result of its enhanced absorption charges. You may be considering, ‘these advantages sounds compelling’, and you’d be right, they are. However, the overwhelming majority of analysis on creatine’s efficacy, including its safety profile and long-term effects on muscle growth and efficiency, has been performed using creatine monohydrate. Consequently, whereas Creatine HCL presents an intriguing alternative, particularly for people who might not tolerate monohydrate properly, the foundational benefits of creatine supplementation as an entire, stay constant throughout each forms. By replenishing ATP ranges more effectively, creatine supplementation allows athletes, bodybuilders and everyday lively people to maintain up larger performance ranges. This interprets to significant enhancements in power, energy output, and muscle endurance, which may help you push tougher during workouts and recuperate faster between sets (Wu, S et al., 2022).
    Different times, the creatine is micronized, or mechanically processed to enhance water solubility. In concept, higher water solubility could improve your body’s capability to soak up it (22). Creatine anhydrous is 100% creatine by weight, whereas the monohydrate type is about 90% creatine by weight. This can enhance exercise efficiency and may even help combat illness (4, 5).
    This transient evaluation will examine each animal and human analysis in relation to the regulation and expression of the creatine transporter (CreaT). The present literature is very preliminary with reference to analyzing how creatine supplementation affects CreaT expression while concomitantly following a resistance coaching routine. In conclusion, it’s prudent that future analysis begin to look at CreaT expression because of creatine supplementation in people in a lot the same method as in animal fashions. Despite the medical research nonetheless, creatine monohydrate does comprise attenuated results such as bloating, cramping, water retention, and poor bioavailability. As A Result Of of those adverse drawbacks, other forms of creatine have been created to address these unwanted facet effects, to have the ability to ship a stronger dose of creatine, in addition to enhance efficiency measures. When administered in a loading protocol with a number of doses of creatine monohydrate per day, an increase in FFM because of water retention can be anticipated [27,28]. First, as previously talked about, a better FFM facilitates higher power outputs [22].
    When it involves the heavyweight battle of creatine supplements, the 2 contenders that constantly go head-to-head are Creatine HCL (hydrochloride) and Creatine Monohydrate. Every creatine has its benefits in relation to chasing these positive aspects, however which one takes the crown? The reply isn’t as simple as you would possibly suppose, however we’ll dissect the rounds of this bout that will help you resolve the best fit for your health routine in an in-depth discussion. It can also be the most well-liked and most cost-effective creatine by-product available on the market.
    We are thrilled to pay attention to that you are experiencing positive results such as improved sleep, psychological clarity, and higher lifting efficiency. Maintain up the good work and let us know if you have any additional suggestions or questions. Whether you’re lifting heavy, sprinting, or pushing through high-intensity workouts, Swolverine’s clinically dosed, totally transparent formula helps you train more durable, recuperate quicker, and construct lean muscle—without the unwanted effects of normal creatine. New forms of creatine should be approved by the MHLW earlier than they can be imported, distributed, and produced in Japan, one requirement being that adequate documentation on the safety and similarity to CM have to be provided.
    Power is very easily and rapidly mobilized from creatine and used to replenish the main energy source which human cells use for his or her functioning (adenosine triphosphate – ATP). Whereas Kre-Alkalyn does have many advantages, such as no have to have a loading phase, and so on., it’s particularly noted for its benefits in enhancing train efficiency. Creatine is among the most well-researched and efficient sports activities dietary supplements to exist today. It’s probably the greatest supplements to increase energy, strength, and peak performance for any athlete at any degree. It primarily promotes lean muscle growth and improved performance without causing extreme water retention. People use creatinol-O-phosphate supplements because they consider these dietary supplements make them stronger, extra muscular and extra capable of recuperate shortly during and after strenuous train.
    Comparable findings have been made with intellectual disability-related illnesses [239]. This bioenergetic deficit is assumed to result in apoptosis and necrosis and ultimately to neuronal degeneration [240]. Due To This Fact, it’s cheap to imagine that an improvement in mitochondrial health could allow a constructive affect on the course of the disease. Table 6 offers a abstract of the extent of proof related to the position of creatine supplementation for neurodegenerative issues [45,234,236]. Initial research recommend that creatine supplementation may be neuroprotective.
    The product is claimed to be the only solubilized form of powdered creatine in the market, making it more bioavailable and steady. Nonetheless, no proof has been revealed to date to substantiate any efficiency or ergogenic benefit from this type of creatine. Tallon et al. (Child and Tallon 2007) compared the soundness of creatine ethyl ester (CEE) face to face with CM and located that CEE was actually much less steady than CM. It was concluded that the addition of the ethyl group to creatine truly decreased acid stability and accelerated its breakdown to creatinine. It is speculated that the methyl ester or ethyl ester groups are higher leaving teams than hydroxyl or water and, due to this fact, suggesting that the degradation into creatinine ought to be rather accelerated.
    Two groups, separated by gender, had a muscle biopsy taken, which was then analyzed for CreaT mRNA, CreaT protein, and whole creatine content material. The results failed to point out any variations between genders in neither complete creatine content material nor CreaT protein quantity, with CreaT protein expression best in kind I fibers than in kind II muscle fibers. Lastly, results concluded that there was an inverse relationship between complete creatine content and CreaT protein content material for females. It was famous that this relationship was additionally very close to being important for males as properly; after an outlier was removed, each genders proved statistically significant. Subsequently, as complete creatine content material increases, the creatine transporter content decreases, and vice versa.
    It contains a high proportion of creatine, often exceeding 99% with minimal additives or fillers. Nitrate, however, is shaped by combining one molecule of creatine and one molecule of nitric acid. It additionally ensures that users get the attainable advantages of the availability of nitric acid, together with creatine.
    The findings of this research highlight the significance of considering supplementation of creatine monohydrate when present process testing for the maximal glycolytic fee. When contemplating the addition of dietary supplements such as creatine monohydrate or creatine phosphate to your routine, it is essential to hunt steering from health professionals. They can present personalised advice primarily based in your health standing, dietary needs, and health objectives. A sports nutritionist or a dietitian can supply insights into how these dietary supplements could be integrated into your total nutrition plan. Creatine phosphate, also referred to as phosphocreatine, is a naturally occurring substance within muscle cells.

    References:

    https://twigaunt0.bloggersdelight.dk/2025/03/19/steroid-cycles-complete-guide-to-everything-you-need-to-know/

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  812. There is a noticeable surge in both energy and endurance throughout the first two weeks of starting the Anavar cycle. Regardless Of its gentle nature, it is important to comply with an acceptable coaching regimen and preserve a proper food plan to acquire optimal outcomes while minimizing potential side effects. You’ll get individuals injecting steroids as a result of it’s perceived as extra excessive and some people think that you just get better results – this isn’t at all times the case.
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    Advanced customers have theflexibility to tailor their Oxandrolone cycles primarily based on their particular goalsand preferences. Dosage for superior customers may range from 60 to a hundred milligramsper day, though it is necessary to notice that greater dosages increase the risk ofside results. Advanced customers may also consider stacking Anavar with other compoundsto synergize effects and achieve desired outcomes. For individuals who haveextensive experience with numerous anabolic steroids and have reached anadvanced level of their health journey, Oxandrolone is usually a valuable additionto their regimen. Advanced users possess a deep understanding of their bodies’responses to totally different compounds and have likely achieved significant gains inmuscle mass, strength, and total efficiency. Anavar, known for its mild natureand favorable risk-to-benefit ratio, can function a flexible software for advancedusers to additional improve their physique and athletic skills.
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    References:

    https://ukcarers.co.uk/employer/anavar-vs-anadrol/

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  816. Whereas Trenbolone pills have the potential to promote muscle gains, combining them with a well-structured food regimen and train program is important to achieve optimal results. Additionally, the use of Trenbolone, whether or not in pill or injectable form, ought to be done responsibly and beneath proper medical steerage to attenuate the risk of unwanted effects. The duration of a Trenbolone cycle depends on the individual’s experience stage, goals, and tolerance.
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